3D Microphysiological System‐Inspired Scalable Vascularized Tissue Constructs for Regenerative Medicine (Adv. Funct. Mater. 1/2022)

Vascularized Tissue Constructs

A major challenge in tissue engineering is the lack of proper vascularization of the fabricated tissue constructs. Microscale technologies, especially microfluidic systems, provide new opportunities to overcome the challenge of developing artificial micro-vasculatures. In this chapter, the application of microfluidic systems for generating vascularized tissue constructs by using microfluidic pl...

3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs.

A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new -avenues for drug screening and fundamental studies of wound...

3D biofabrication strategies for tissue engineering and regenerative medicine.

Over the past several decades, there has been an ever-increasing demand for organ transplants. However, there is a severe shortage of donor organs, and as a result of the increasing demand, the gap between supply and demand continues to widen. A potential solution to this problem is to grow or fabricate organs using biomaterial scaffolds and a person's own cells. Although the realization of thi...

Tissue Engineered Scaffolds in Regenerative Medicine

Stem cells are self-renewing cells that can be differentiated into other cell types. Conventional in vitro models for studying stem cells differentiation are usually preformed in two-dimensional (2D) cultures. The design of three-dimensional (3D) in vitro models which ideally are supposed to mimic the in vivo stem cells microenvironment is potentially useful for inducing stem cell derived tissu...

Materials and Wireless Microfluidic Systems for Electronics Capable of Chemical Dissolution on Demand (Adv. Funct. Mater. 92015)